How could you differentiate between a Y-linked trait and an imprinted trait that is transmitted by males?
Y-linked trait and an imprinted trait?
Basic Mendelian disorders
Since normal males are XY and females XX,
Y-linked disorders are usually related to the SRY (Sex-determining Region Y) and usually have to do with
with humans with chromosome duplication XXY or XXXY or defects with sex determining region
Maternal (Mitochondrial) Inheritance
Diseases of the mitochondria are inherited in one of two ways: through the maternal lineage
or as autosomal disorders
Imprinting
Finally, For the vast majority of autosomal genes, expression may occur from either allele.
However, a small proportion (%26lt;1%) of genes are imprinted, meaning that expression occurs
from only one allele. The expressed allele is dependent upon its parental origin. For
some alleles only one parents allele is recognized and the other parent's is silenced
Imprinting is a huge problem with the cloning of mammals
Subscribe to:
Post Comments (Atom)
No comments:
Post a Comment