Monday, November 16, 2009

X-linked traits?

What are some differences between the inheritance patterns of X-linked traits and traits controlled by genes on other, autosomal, chromosomes?

X-linked traits?
If it is on the X, a male will get any recessive diseases on it because there are no dominant traits to override the disease. Therefore, if a mother is a carrier of a recessive disease and the father doesn't have the disease, a son has a 50% chance of acquiring the disease, while a daughter has a 0% chance, only a 50% chance of being a carrier. If a father has a dominant X-linked gene, a son has a 0% chance of getting it and a female has a 100% chance of getting it. Compare this to normal situations, where a dominant disease would have a 50% chance of getting passed on male or female. A recessive disease would have a 0% chance if only the female had it.





Diseases caused by X-Linked genes:


Colorblindness--recessive


Hemophilia--recessive


Duchenne Muscular Dystrophy--recessive


Incontinentia pigmenti--dominant





Most are recessive because dominant diseases generally get slowly weeded out of the population.

polish

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