Friday, April 16, 2010

Gene problem - X-linked?

Hemophilia is inherited as an X-linked recessive. A woman has a brother with this defect and a mother and father who are phenotypically normal. What is the probability that this woman will be a carrier if she herself is phenotypically normal?

Gene problem - X-linked?
50 percent. Details: Mom = xX, Dad = XY. Brother = xY. (the little x is the "bad" one.) So sister gets either XX or xX. (The X on the left is from Mom, the X on the right is from Dad.)


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